新金沙app下载|首頁|欢迎您

最新文章

热门文章

湛洋老师简介

时间: 2021/09/09   作者:   点击:

湛洋老师-个人简历

姓名

湛洋

性别

2017-12-11-因公护照用

籍贯

长沙

出生年月

1989.10

学历

博士

职称

讲师

Email

yangzhan@hunau.edu.cn

电话

15874174276

 

招生

意向

招生类型

招生学科

研究方向

 

临床兽医学

兽医临床微生物学及功能蛋白质的研究

兽医硕士

兽医学

兽医临床分子诊断及流行病学调查

 

教育

经历

2012.09-2017.07,湖南农业大学,临床兽医学博士(硕博连读) 

2014.09-2015.02,美国国立卫生研究院,访问学者

2008.09-2012.07,湖南农业大学,动物医学学士

 

研究

项目

1.   湖南省农业领域重点研发项目,2019NK2171,非洲猪瘟精准、高灵敏和超快速检测新技术的创制及应用-子项目,2019/01-2021/125万,在研,主持

2.   湖南省教育厅科学研究项目,18B092,猪圆环病毒2 型核衣壳五倍轴区域附近氨基酸残基的生物学功能研究,2019/01-2020/125万,在研,已结题,主持

3.   湖南农业大学校科学基金项目,17QN10,猪圆环病毒2型核衣壳蛋白(Cap)羧基端PXXP motif免疫原性的研究,2017/10-2019/120.6万,已结题,主持

4.   湖南省研究生科研创新项目,CX2016B285,猪圆环病毒2型核衣壳蛋白(Cap)羧基端氨基酸残基的功能研究,2016/01-2017/121.6万元,已结题,主持

5.   国家自然科学基金项目,31571432,非肌性蛋白IIA突变引起MYH9相关疾病的分子机制研究,2016/01-2019/1278万元,已结题,参与

 

发表

论文

1. Yang Zhan#, Wanting Yu#, Xiong Cai, Xinnuo Lei, Hongyu Lei, Aibing Wang, Yujie Sun, Naidong Wang, Zhibang Deng, Yi Yang*. The carboxyl terminus (CT) of the PCV2 capsid protein (Cap) is critical to VLP assembly, cell entry, and propagation. J Virol, 2020, 94(9): e00042-20.

2.Yang Zhan, Naidong Wang, Zhe Zhu, Zhanfeng Wang, Aibing Wang, Zhibang Deng, Yi Yang*. In silico analyses of antigenicity and surface structure variation of an emerging PCV2b mutant, prevalent in southern China from 2013 to 2015. J Gen Virol, 2016, 97(4):922-933.

3. Naidong Wang#, Yang Zhan#, Aibing Wang, Lijie Zhang, Reza Khayat, Yi Yang*. In silico Analysis of Surface Structure Variation of PCV2 Capsid Resulted from Loops Mutation of Its Capsid Protein (Cap). J Gen Virol, 2016, 97(12): 3331-3344.

4. Yi Hu#, Yang Zhan#, Dongliang Wang, Xiaohong Xie, Tanbin Liu, Wei Liu, Naidong Wang, Zhibang Deng, Hongyu Lei, Yi Yang, and Aibing Wang*. Evidence of natural co-infection of PCV2b subtypes in vivo. Arch Virol, 2017, 162(7): 2015-2020.

5. Wanting Yu, Yang Zhan, Boxin Xue, Yanpeng Dong, Yanfeng Wang, Ping Jiang, Aibing Wang, Yujie Sun* and Yi Yang*. Highly efficient cellular uptake of a cell-penetrating peptide (CPP) derived from the capsid protein of porcine circovirus type 2. J Biol Chem, 2018, 293(39): 15221-15232.

6. Yi Hu, Xiong Cai, Yang Zhan, Xiaomin Yuan, Tanbin Liu, Lei Tan, Yalan Li, Lijie Zhang, Lingchen Yang, Wei Liu, Zhibang Deng, Naidong Wang, Yi Yang, Shiyin Guo* and Aibing Wang*. Truncated Rep protein of porcine circovirus 2 (PCV2) caused by a naturally occurring mutation reduced virus replication in PK15 cells. BMC Vet Res. 2019, 15(1):248.

7. Yan Zhang, Zhanfeng Wang, Yang Zhan, Qian Gong, Wanting Yu, Zhibang Deng, Aibing Wang, Yi Yang, Naidong Wang*. Generation of E. coli-derived virus-like particles of porcine circovirus type 2 and their use for an indirect IgG Enzyme-Linked Immunosorbent Assay. Arch Virol, 2016, 161(6): 1485-1491.

8. Qian Gong#, Yi Hu#, Yang Zhan, Dongliang Wang, Naidong Wang, Guanyu Chen, Aibing Wang, Yi Yang*. Complete Genome Sequence of Porcine Circovirus Strain YiY-3-2-H5 with a novel insertion, Isolated from Hunan Province, China. Genome Announc, 2016, 4(2).

9. Zhe Zhu#, Naidong Wang#, Yang Zhan, Zhanfeng Wang, Aibing Wang, Zhibang Deng*, Yi Yang*. 2015. Complete genome sequence of porcine circovirus strain 102 with a novel mutation, isolated from hunan province, china. Genome Announc, 2015, 3(3).

10. Jie Cai, Xiaohong Xie, Yi Hu, Yang Zhan, Wanting Yu, Aibing Wang, Naidong Wang*. Generation of PCV2 in PK15 cells transfected with recombinant baculovirus containing a 1.1 copy of the PCV2 genome. Acta Veterinaria Hungarica, 2017, 65(2): 278-290.

11. Dongliang Wang, Jinhui Mai, Wenfeng Zhou, Wanting Yu, Yang Zhan, Naidong Wang, Neal D. Epstein*, Yi Yang*. Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design. Vaccines (Basel).2020, 8(3): 355.

12. Lingchen Yang, Di Tu, Naidong Wang, Zhibang Deng, Yang Zhan, Wei Liu, Yi Hu, Tanbin Liu, Lei Tan, Yalan Li, Shiyin Guo*, Aibing Wang*.The protective effects of DL-Selenomethionine against T-2/HT-2 toxinsinduced cytotoxicity and oxidative stress in broiler hepatocytes. Toxicol In Vitro. 2019, 54:137-146.

13. Jiaxin Zhang, Xinnuo Lei, Dongliang Wang, Yifan Jiang, Yang Zhan, Meng Li, Yawen Zhou, Yiwen Qin, Jue Liu, Aibing Wang, Yi Yang, Naidong Wang. Inhibition of Abl or Src tyrosine kinase decreased porcine circovirus type 2 production in PK15 cells. Res Vet Sci. 2019. 124:1-9.

14. Tanbin Liu#, Yi Hu#, Shiyin Guo, Lei Tan, Yang Zhan, Lingchen Yang, Wei Liu, Naidong Wang, Yalan Li, Yingfan Zhang, Chengyu Liu, Yi Yang, Robert S. Adelstein, Aibing Wang*. Identification and characterization of MYH9 locus for high efficient gene knock-in and stable expression in mouse embryonic stem cells. PLoS One, 2018, 13(2): e0192641.

15. Naidong Wang, Yan Zhang, Xinnuo Lei, Wanting Yu, Yang Zhan, Dongliang Wang, Jiaxin Zhang, Aibing Wang, Lehui Xiao, Ping Jiang*, Yi Yang*. Optimized conditions for preserving stability and integrity of porcine circovirus type2 virus-like particles during long-term storage. Journal of Virological Methods, 2017, 243: 146-150.

16. Dongliang Wang, Sujiao Zhang, Yawen Zou, Wanting Yu, Yifan Jiang, Yang Zhan, Naidong Wang*, Yanpeng Dong, Yi Yang*. Structure-Based Design of Porcine Circovirus Type 2 Chimeric VLPs (cVLPs) Displays Foreign Peptides on the Capsid Surface. Front Cell Infect Microbiol, 2018, 8: 232.

17. Naidong Wang, Sujiao Zhang, Dongliang Wang, Fuqiang Li, Lin Liang, Xiuli Li, Yawen Zou, Yang Zhan, Guanyu Chen, Wanting Yu, Zhibang Deng, Di Tu*, Shangjin Cui*. Protective humoral immunity in guinea pigs induced by PCV2 virus-like particles displaying the B cell linear epitope (228QQITDA233) of PPV1. Vet Microbiol, 2019, 235: 86-92.

18. Lingchen Yang, Di Tu, Yingxin Wu, Wei Liu, Yi Hu, Tanbin Liu, Lei Tan, Yalan Li, Hongyu Lei, Yang Zhan, Naidong Wang, Zhibang Deng, Shiyin Guo*, Aibing Wang*. Distribution and persistence of residual T-2 and HT-2 toxins from moldy feed in broiler chickens. Toxicon. 2020, 178:82-91.

19. Lei Tan, Yalan Li, Jiayi He, Yi Hu, Xiong Cai, Wei Liu, Tanbing Liu, Jiaoshun Wang, Zhoumian Li, Xiaoming Yuan, Yang Zhan, Lingchen Yang, Zhibang Deng, Naidong Wang, Yi Yang, Aibing Wang*. Epidemic and genetic characterization of porcine epidemic diarrhea virus strains circulating in the regions around Hunan, China, during 2017-2018. Arch Virol, 2020, 165(4):877-889.

20. 黄坤,王东亮,邹亚文,王乃东,董彦鹏,湛洋*. 猪圆环病毒2d 型的分子生物学特征和流行病学研究进展. 经济动物学报. 2019, 23(01): 51-56.

21. 贺延峰,王东亮,邹亚文,董彦鹏,王乃东,湛洋*. 湖南地区猪圆环病毒2型的分离与鉴定. 中国兽医科学. 2019, 49(02): 213-219.

22. 张露华,李周勉,唐祎依,蔡云凤,田唯嘉,黄坤,王东亮,王乃东,湛洋*. 猪圆环病毒2型和3型双重PCR方法的建立与优化. 黑龙江畜牧兽医. 2020(05): 71-76.

23. 湛洋,王东亮,王乃东,蒋一凡,黄坤,崔尚金,姜平,杨毅*. 猪圆环病毒3型检测及其Cap结构序列和抗原性预测分析. 畜牧兽医学报. 2017, 48(6): 1076-1084.

24. 湛洋,胡意,王东亮,蔡杰,邓治邦*. PCV2a-ORF3基因突变株感染性克隆的构建. 中国预防兽医学报. 2017, 39(5): 351-355.

25. 王东亮,湛洋,胡意,雷昕诺,庞培,张素娇,王爱兵,杨毅,王乃东*. 猪圆环病毒2型衣壳蛋白的Loops结构及病毒样颗粒制备的研究进展.中国兽医学报. 2018(1): 235-240.

26. 余婉婷, 湛洋, 雷昕诺, 张颜, 谢小红, 王乃东, 邓治邦, 王爱兵, 杨毅*. 猪圆环病毒2型病毒样颗粒的研究及应用. 中国畜牧兽医文摘. 2015, 31(5): 57-58.

27. 陈指龙,邓吉平,湛洋,林 源,王昌建,谭艳芳,杨青*,袁安文*. 猪圆环病毒2型湖南株的分离鉴定与进化分析. 中国兽医科学. 2020, 50(12):1522-1530.

28. 李亚兰, 袁晓民, 湛洋, 杨凌宸, 胡意, 谭磊, 刘谭彬, 郭时印, 王爱兵*.猪流行性腹泻病毒检测方法的研究进展. 中国兽医科学. 2019, 49(03): 347-354.

29. 谷婷,庞培,湛洋,奉湘艳,徐奇,刘沅,贺延峰,方满新,邓治邦. PCV2病毒载量与病理损伤的相关性. 中国兽医学报. 2018, 38(04): 625-630+649.

30. 王占锋, 朱哲, 湛洋, 邓治邦, 王爱兵, 杨毅, 王乃东*. 猪圆环病毒2型湖南分离株HNLYYA1全基因组的多引物滚环扩增和序列分析. 中国兽医科学. 2016(4): 454-460.

31. 王教顺, 王东亮, 张素姣, 江游, 湛洋, 袁晓民, 邓治邦. PCV2bPCV2d病毒样颗粒交叉免疫保护效力的评估[C]. 中国畜牧兽医学会兽医病理学分会, 2019:22.

32. 张佳鑫, 蒋一凡, 雷昕诺, 秦艺文, 湛洋, 王乃东*. SrcAbl酪氨酸蛋白激酶家族参与病原微生物感染的研究进展. 微生物学通报. 2019, 46(10): 2781-2786.

33. 张素姣, 王东亮, 李萌, 蒋一凡, 湛洋, 王乃东*. Loop EF区嵌合猪细小病毒B细胞表位对猪圆环病毒2型病毒样颗粒组装的影响. 中国兽医科学. 2019, 49(02): 176-182.

34. 李周勉, 邹亚文, 蒋一凡, 胡意, 秦艺文, 李萌, 湛洋, 王东亮, 王乃东*. 猪圆环病毒3Cap蛋白序列的生物信息学研究. 经济动物学报. 2020, 24(01): 9-16.

35湛洋,彭涛,刘磊,文利新*. 提高兽医临床诊断学课程教学效果的途径探讨[J]. 黑龙江畜牧兽医, 2020(12): 155-157.

 

获奖

成果

2020.04  2019年度湖南省自然科学奖二等奖(第二完成人)(猪圆环病毒2型衣壳蛋白loop结构及其展示外源抗原表位的研究)

2016.12  “大北农杯”第一届全国农林院校研究生学术科技作品一等奖(新型PCV2b突变毒株表面结构的模拟及PCV2重组进化分析)

2016.06  美国微生物学大会优秀博士生奖学金(In silico analyses of antigenicity and surface structure variation of an emerging PCV2b mutant

 

社会

兼职

第九届中国畜牧兽医学会兽医内科与临床诊疗学分会理事 (201908-202307)

 

点击下载文件:
XML 地图